The Gaublomme lab develops optical pooled CRISPR screens with multi-omic in situ readout to understand cellular function and intercellular communication.
The Gennarino lab is an RNA Neurobiology lab that moves between patients, animal models, and wet lab experiments to understand how defects in RNA-binding proteins and post-transcriptional RNA processing cause neurological diseases.
The Maniatis lab is interested in understanding fundamental mechanisms of transcription and RNA splicing in the nervous system, and how these mechanisms bear on neuronal connectivity and neurodegenerative diseases.
The Tong lab uses structural biology techniques to study the molecular mechanism of RNA 3'-end processing, 5' decapping, degradation and related events
The Zaccara lab is dedicated to investigating the fundamental mechanisms that regulate mRNA fate in both normal and disease states, with a specific focus on understanding the role of RNA modifications